Annals of Pediatric Gastroenterology and Hepatology ISPGHAN

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VOLUME 3 , ISSUE 2 ( April-June, 2021 ) > List of Articles

Clinical Synopsis

Anti-Tubercular Drugs Induced Hepatotoxicity

Citation Information : Anti-Tubercular Drugs Induced Hepatotoxicity. Ann Pediatr Gastroenterol Hepatol 2021; 3 (2):1-3.

DOI: 10.5005/jp-journals-11009-0074

License: CC BY-NC 4.0

Published Online: 06-07-2022

Copyright Statement:  Copyright © 2021; The Author(s).


Abstract

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  1. Saukkonen JJ, Cohn DL, Jasmer RM, et al; ATS (American Thoracic Society) Hepatotoxicity of Antituberculosis Therapy Subcommittee. An official ATS statement: hepatotoxicity of antituberculosis therapy. Am J Respir Crit Care Med. 2006; 174:935-952.
  2. Tostmann A, Boeree MJ, Aarnoutse RE, de Lange WC, van der Ven AJ, Dekhuijzen R. Antituberculosis drug-induced hepatotoxicity: concise up-to-date review. J Gastroenterol Hepatol. 2008 Feb;23 (2):192-202. doi: 10.1111/j.1440-1746.2007.05207.x. Epub 2007 Nov 6. PMID: 17995946.
  3. Desrochers D, González-Peralta RP, McClenathan DT, et al. Isoniazidinduced severe hepatotoxicity: an infrequent but preventable cause of liver failure in children treated for latent tuberculosis infection. Clin Med Insights Pediatr. 2011;5:9-13.
  4. Gafar F, Arifin H, Jurnalis YD, Yani FF, Fitria N, Alffenaar JC, Wilffert B. Antituberculosis Drug-induced Liver Injury in Children: Incidence and Risk Factors During the Two-month Intensive Phase of Therapy. Pediatr Infect Dis J. 2019 Jan;38 (1):50-53. doi: 10.1097/INF.0000000000002192. PMID: 30234790.
  5. Mahmood K, Hussain A, Jairamani KL, et al. Hepatotoxicity with antituberculosis drugs: the risk factors. Pak J Med Sci. 2007; 23:33-38.
  6. Indumathi CK, Sethuraman A, Jain S, Krishnamurthy S. Revised Antituberculosis Drug Doses and Hepatotoxicity in HIV Negative Children. Indian J Pediatr. 2019 Mar;86 (3):229-232. doi: 10.1007/s12098-018-2812-z. Epub 2018 Dec 4. PMID: 30515702.
  7. World Health Organization. Guidance for National Tuberculosis Programmes on the Management of Tuberculosis in Children. 2nd ed. Geneva, Switzerland: World Health Organization; 2016.
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