Pediatricians/pediatric gastroenterologists should be aware of the causes of massive hepatomegaly in children and be able to differentiate benign diseases from those with a worse prognosis and evaluate accordingly. Clinical evaluation is of extreme importance, with keen attention to agewise etiologies and clinical pointers. Most disorders causing massive hepatology in children are potentially treatable with favorable outcomes if detected and treated early. This review discusses the approach for the evaluation of a child presenting with massive hepatomegaly.
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