Annals of Pediatric Gastroenterology and Hepatology ISPGHAN

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VOLUME 1 , ISSUE 2 ( April-June, 2019 ) > List of Articles


Primary Diffuse Large B Cell Lymphoma of Colon Presenting as Chronic Diarrhea in a 3 Year Old Child - Case Report

Suraj Uppalapati, Prashant Kanni, Praveen Mathew, Manjunath Patil, Praveen Kumar

Keywords : GI Lymphoma, Chronic Diarrhea

Citation Information : Uppalapati S, Kanni P, Mathew P, Patil M, Kumar P. Primary Diffuse Large B Cell Lymphoma of Colon Presenting as Chronic Diarrhea in a 3 Year Old Child - Case Report. Ann Pediatr Gastroenterol Hepatol 2019; 1 (2):11-15.

DOI: 10.5005/jp-journals-11009-0011

License: CC BY-NC 4.0

Published Online: 04-07-2022

Copyright Statement:  Copyright © 2019; The Author(s).


A 3 year old baby boy presented to hospital with a 2 months history of watery diarrhea (8- 10 episodes per day) associated with abdominal pain, weight loss and swelling of face and limbs. Rehydration and electrolytic balance were restored with intravenous fluid therapy along with cover of antibiotics but diarrhea was worsening. Patient was planned for gastroscopy and ileo- colonoscopy with biopsies from duodenum and ileum. Gastroscopy was normal but colonoscopy showed ileal scalloping and transverse colon showed short segment stricture of approx. 5 cms with multiple ulcers. CT imaging showed a structuring mass involving the transverse colon and few adjacent jejunal loops with enlarged lymph nodes. Histopathological examination of the biopsies from transverse colon showed dense lymphoid aggregates. Hence Bone marrow aspiration and IHC panel of markers were advised. BMA was normal but IHC staining revealed Primary Diffuse large B cell Lymphoma of large intestine.

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